Reply To: any one used Ecdysterone

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February 3, 2009 at 1:58 pm #7725

I just had a quick read up on it…

It seems a little too good to be true by all the things that are said about it but there may be some of the benefits just not all. Humans do not have the receptors for this either, but supposedly there is some uptake. It is hard to find studies on it in humans, lots on insects as it is an integral insect chemical. It does make female lobsters more aggresive than normal if that interests you.

Here is some info below:

A study done on mice:
Daily oral administration of 20HE (10 mg/kg for 13 weeks) ameliorated obesity and insulin resistance in C57BL/6J mice fed a high-fat diet and produced a significant decrease of body weight gain and body fat mass compared to non-treated animals as demonstrated by dual-energy x-ray absorptiometry analysis. In addition, plasma insulin levels and glucose tolerance were significantly lowered by 20HE treatment.

A study on trained males:
Using 200 mg of E/day, No significant differences (p > 0.05) were observed in training adaptations among groups in the variables FFM, percent body fat, bench press 1 RM, leg press 1 RM or sprint peak power. Anabolic/catabolic analysis revealed no significant differences among groups in active testosterone (AT), free testosterone (FT), cortisol, the AT to cortisol ratio, urea nitrogen, creatinine, the blood urea nitrogen to creatinine ratio.

Another study on mice:
The effect on fiber size was modified by the distance from the site of the treatment and the presence of a regenerating soleus muscle in the animal. Besides the fiber size, 20E also increased the myonuclear number in the fibers of normal and regenerating muscles, suggesting the activation of satellite cells. According to our results 20E may provide an alternative for substitution of anabolic-androgenic steroids in therapeutic treatments against muscle atrophy.

That is all I have got, one direct study in humans which has a low dosage compared to UB’s suggestions but does not make any positive changes. The rat studies are interesting, I think they are both from hungary but they are rats and not humans.

Lets get UB to go off it for a month or so do some blood tests and strength tests and then see how he does on it. 🙂